Campylobacter fetus fetus abortions in vaccinated ewes - vaccine history and ongoing development

Authors: Marchant RM
Publication: New Zealand Veterinary Journal, Volume 48, Issue 5, pp 158, Oct 2000
Publisher: Taylor and Francis

Animal type: Livestock, Production animal, Ruminant, Sheep
Subject Terms: Abortion/stillbirth, Animal remedies/veterinary medicines, Bacterial, Zoonosis, Infectious disease, Reproduction, Immune system/immunology, Reproduction - female, Disease/defect, Vaccination, Public health
Article class: Correspondence

---

Abstract: Correspondence: Campylobacter fetus fetus abortions in vaccinated ewes - vaccine history and ongoing development. Thank you for the opportunity to comment on the communication reporting Campylobacter abortions in vaccinated ewes by Fenwick et al. (New Zealand Veterinary Journal 48, 155-7, 2000). The vaccine Campylovexin (Schering-Plough Animal Health), an inactivated bacterin containing Campylobacter fetus subspecies fetus antigens, has been available since the early 1980`s. This single-strain vaccine (strain A5915) was manufactured from cultures of C. fetus fetus isolated from a field case from Mid-Canterbury. Company records show that Campylovexin was extensively tested in the field in 1980 and 1981, and provided good protection from Campylobacter abortion on properties where natural challenge occurred. As a single-strain vaccine, its ability to protect against other field strains of C. fetus fetus was not known. During the development and use of the vaccine in the early 1980`s, the majority of isolates from C. fetus fetus abortion cases throughout New Zealand were identified as…

---