Dihydrostreptomycin or streptomycin in combination with penicillin G in dairy cattle therapeutics: A review and re-analysis of published data Part 1: Clinical pharmacology

Authors: Hanlon D, Whittem T
Publication: New Zealand Veterinary Journal, Volume 45, Issue 5, pp 178-184, Oct 1997
Publisher: Taylor and Francis

Animal type: Cattle, Livestock, Production animal, Ruminant
Subject Terms: Animal remedies/veterinary medicines, Anthelmintics, Parasite control, Parasites - internal, Pharmacology, Treatment/therapy
Article class: Review Article

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Abstract: Combination formulations of penicillin G salts and dihydrostreptomycin were developed during the 1960s and are currently marketed in New Zealand for parenteral and intramammary use in dairy cattle. In this paper, the clinical indications and efficacy, pharmacokinetics and potential for antimicrobial synergy of penicillin and dihydrostreptomycin or streptomycin, when combined, are discussed.

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