Serum glutathione peroxidase activity reflects short-term increases in selenium intake in goats

Authors: Williamson NB, Thompson KG, Wichtel JJ
Publication: New Zealand Veterinary Journal, Volume 44, Issue 4, pp 148-150, Aug 1996
Publisher: Taylor and Francis

Animal type: Goat, Livestock, Production animal, Ruminant
Subject Terms: Biochemistry/chemistry, Clinical pathology, Diagnostic procedures, Diet/rations/food, Nutrition/metabolism, Selenium, Trace elements
Article class: Short Communication

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Abstract: The objective of this study was to determine if serum glutathione peroxidase activity reflects short-term changes in the selenium status of goats. Angora goat kids (n=14) were fed pelleted luceme containing 20 µg/kg of selenium, and treated orally with either selenium (0.1 mg/kg of liveweight weekly, as sodium selenate) or de-ionised water. Serum activity of glutathione peroxidase was increased in response to supplementation and differed from that of controls within 24 hours of supplementation. The change in serum glutathione peroxidase activity during the 21 days after the start of weekly supplementation closely followed changes in serum selenium concentration. The results of this study suggest that serum glutathione peroxidase activity reflects the short-term improvement in the selenium status of Angora goat kids following oral supplementation with sodium selenate.

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