Contrast between the pharmacokinetics of two formulations of cephalexin after intramuscular administration in cattle

Authors: Slacek B, Whittem T
Publication: New Zealand Veterinary Journal, Volume 44, Issue 4, pp 145-147, Aug 1996
Publisher: Taylor and Francis

Animal type: Cattle, Livestock, Production animal, Ruminant
Subject Terms: Animal remedies/veterinary medicines, Antibiotics, Treatment/therapy, Bacterial, Infectious disease, Disease/defect, Alimentary system/gastroenterology, Notifiable organisms/exotic disease, Pharmacology, Respiratory system, Zoonosis, Public health
Article class: Short Communication

---

Abstract: Two commercial formulations of cephalexin were administered intramuscularly to five heifers and five bulls in a balanced crossover design. Statistically significant and clinically important differences were detected between the two formulations of cephalexin. These results suggest that 24 h dose intervals would be appropriate with only one of the formulations and that the recommended dose rates for each product may need to be reviewed.

---