The efficacy of a Leptospira interrogans serovars pomona and copenhageni and L. borgpetersenii serovar hardjo vaccine in cattle

Authors: Taylor C, Slacek B, Palit A, Alexander AM
Publication: New Zealand Veterinary Journal, Volume 44, Issue 2, pp 64-66, Apr 1996
Publisher: Taylor and Francis

Animal type: Cattle, Livestock, Production animal, Ruminant
Subject Terms: Animal remedies/veterinary medicines, Bacterial, Clinical pathology, Diagnostic procedures, Immune system/immunology, Zoonosis, Disease/defect, Infectious disease, Vaccination, Public health
Article class: Scientific Article

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Abstract: An experimental, trivalent, bovine, leptospiral vaccine, containing inactivated Leptospira interrogans serovars pomona and copenhageni and L. borgpetersenii serovar hardjo Hardjobovis, was developed. The experimental vaccine was shown to protect hamsters against virulent challenge with each of the component serovars. In a serological efficacy test in cattle, the experimental vaccine was compared for bioequivalence with a similar product, registered in New Zealand for veterinary use. The experimental vaccine induced higher titres in cattle than the latter mentioned product.

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