Evaluation of the efficacy of doramectin against an artificial infection of Dictyocaulus viviparus in calves

Authors: Pomroy WE, Whelan NC, Alexander AM, Charleston WAG
Publication: New Zealand Veterinary Journal, Volume 43, Issue 1, pp 21-22, Feb 1995
Publisher: Taylor and Francis

Animal type: Cattle, Livestock, Production animal, Ruminant
Subject Terms: Animal remedies/veterinary medicines, Anthelmintics, Parasite control, Parasites - internal, Treatment/therapy, Respiratory system, Nematode
Article class: Scientific Article

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Abstract: Three groups of eight Friesian calves, reared parasite-free, were experimentally infected with 1000 infective larvae of Dictyocaulus viviparus. Two groups were injected subcutaneously with 1% doramectin at 0.2 mg/kg body weight, one group 5 days after infection and the other 25 days after infection. A third group served as untreated controls. Faecal samples were examined for lungworm larvae on days 28, 32, 33, 34 and 35 after infection; the calves were killed and necropsied 39 or 40 days after infection and any lungworms present recovered and counted. Doramectin proved 100% effective against both 5-day-old and mature D. viviparus infections.

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