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Adrenal-associated changes in experimental sporidesmin poisoning of sheep

Authors: Payne E, Smith BL
Publication: New Zealand Veterinary Journal, Volume 39, Issue 2, pp 46-49, Jun 1991
Publisher: Taylor and Francis

Animal type: Livestock, Production animal, Ruminant, Sheep
Subject Terms: Endocrine/autocrine/paracrine, Inflammation, Integument/skin/wool/hair/fur/feather, Disease/defect, Mycotoxicosis, Liver/hepatic disease, Fungal/yeast, Photosensitivity, Toxicology
Article class: Scientific Article

Abstract: Sporidesmin-dosed hoggets which developed photosensitisation were shown to have enlarged adrenal glands and premature involution of the thymus. These sheep also developed high concentrations of plasma cortisol after the onset of photosensitisation. Sporidesmin-dosed sheep which did not show photosensitisation showed less or no adrenal associated changes.

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