beta -Mannosidosis in a Salers calf: a new storage disease of cattle

Authors: Bayliss SL, Vidler BM, Jolly RD, Thompson KG, Orr MB, Healy PJ
Publication: New Zealand Veterinary Journal, Volume 38, Issue 3, pp 102-105, Sep 1990
Publisher: Taylor and Francis

Animal type: Cattle, Livestock, Production animal, Ruminant
Subject Terms: Genetics, Inherited disease/conditions, Nervous system/neurology, Pathology
Article class: Scientific Article

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Abstract: A storage disease characterised by widespread vacuolation of cells throughout the body was diagnosed in a newborn calf of the Salers breed. Extraction and analyses of water soluble material showed that the storage material was oligosaccharide in nature and was probably derived from the core region of the heterosaccharide moiety of glycoproteins. Glycosidase analyses showed that the disease was due to a deficiencv of acidic β-mannosidase.

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