Amino acids in bovine sera

Authors: Hoogenboom JJL, Falloon MN, Rammell CG
Publication: New Zealand Veterinary Journal, Volume 36, Issue 2, pp 96-98, Jun 1988
Publisher: Taylor and Francis

Animal type: Cattle, Livestock, Production animal, Ruminant
Subject Terms: Biochemistry/chemistry, Nervous system/neurology, Inherited disease/conditions, Disease/defect, Clinical pathology, Diagnostic procedures, Congenital disease, Liver/hepatic disease, Metabolic disease, Poisoning - plant, Toxicology
Article class: Correspondence

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Abstract: Certain metabolic disorders are associated with changes in blood amino acid concentrations. In particular, hepatic disease causes an increase in the aromatic amino acids (AAAs), phenylalanine and tyrosine, relative to the branched chain amino acids (BCAAs), isoleucine, leucine and valine while maple syrup disease has the opposite effect. Blood amino acid concentrations are also affected by nutritional plane. Developments in analytical methodology have now made it practical to provide a diagnostic service for amino acids in biological specimens so a study was carried out to provide required reference data for cattle. Serum samples were obtained over a wide geographical area from 2.5 mixed sex (lOM, 15F) and age, clinically normal cattle and stored at -20°C until analysed. Amino acid concentrations were determined by capillary gas-liquid chromatography of their…

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